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MedRxiv, Cavalcanti AB, Zampieri FG, Rosa RG, Azevedo LCP, Veiga VC, Avezum A, Damiani LP, Marcadenti A, et al

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PMID: 25294634

These agents should be designed to exploit the unique metabolic vulnerabilities of GBM cells, including their altered iron metabolism and redox homeostasis

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Several studies have shown that tumor necrosis factor alpha stimulated gene-6 (TSG-6) attenuates inflammatory cascades by inhibiting activation of the TLR2/NF-kappa B signaling pathway (Liu et al., 2014)