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Eventually, GABA is removed from the system by converting it into succinate, which is then used in the Krebs cycle in the mitochondria to make ATP.[ref] The enzyme succinic semialdehyde dehydrogenase ( ALDH5A1 gene) is needed to convert GABA into succinate.[ref] Rare genetic mutations in the ALDH5A1 gene cause succinic semialdehyde dehydrogenase deficiency, which decreases the breakdown of GABA

Brian Stamm, MD, MSc: Nothing to disclose

Through advanced diagnostics, we can identify factors such as heavy metal toxicity, nutrient deficiencies, or inflammation that may be contributing to your symptoms

This results in faster bioavailability, potentially accelerating the onset of its regenerative and anti-inflammatory properties, key areas of interest in clinical and preclinical research

doi: 10.1097/00000658-200107000-00014 32 WangHXPanWZhengLZhongXPTanLLiangZet al