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Sourcing both compounds from a single supplier can reduce lot-to-lot documentation variability when the peptide itself is the variable under study, a practical consideration addressed in the protocol design section

B 12 levels were lower and folate levels were higher in women who were subsequently diagnosed to have GDM, around 27 weeks of gestation

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Known risk factors for methotrexate toxicity include dosing errors, metabolic syndrome, hypoalbuminemia, renal dysfunction, lack of folate supplementation, and the concomitant use of drugs that interfere with methotrexate metabolism

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