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doi: 10.1016/j.lfs.2006.12.024 59 ZhangLWuWT

No standalone-vs-combination equivalence

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(III) The design of a GSH-responsive and -exhausting drug delivery system can achieve tumor specific ablation to a certain extent

Consistently, GSH depletion or silencing of Fe-S cluster-associated GLRXs disrupts mitochondrial redox balance, promotes iron overload, and sensitizes cancer cells to ferroptosis 133,134