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reported that patients with ovarian cancer, who are carriers of glutathione-S-transferase class ( GSTM1)-null genotype or carriers of non- GSTM1-wt/GSTT1-wt genotypes, when treated with both paclitaxel and cisplatin, present higher mean survival time [59], suggesting a role for GSH in paclitaxel resistance also

In the NAC cohort, patients predicted to be NAC responders based on tumor biomarker expression exhibited prolonged OS ( P = 0.084) and PFS ( P = 0.104), though with marginal statistical significance (Fig