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1g and Extended Data Fig

GPX4 positivity was significantly correlated with age ( P = 0.0292), and bone marrow involvement ( P = 0.0406) (Table 2)

Although iron chelators such as deferoxamine (DFO) and deferiprone (DFP) have been shown to reduce ferroptosis-mediated damage in other diseases, they have not been well-studied in diabetes in human subjects

Metabolomic analysis showed major changes in lipids, amino acids, and metabolites linked to the gut microbiome, concordant with transcriptional changes identified through pathway analysis within liver, muscle, and adipose tissues

Zhyzhneuskaya SV, Al-Mrabeh A, Peters C et al (2020) Time course of normalization of functional -cell capacity in the diabetes remission clinical trial after weight loss in type 2 diabetes