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Description

The process of myocardial relaxation (diastole) depends on the rate of pumping of calcium ions from the cytoplasm by calcium pumps (SERCA) into the sarcoplasmic reticulum and the efficiency of ATP synthesis by mitochondria

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The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs

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