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To overcome these limitations, advanced drug delivery systems, particularly nanotechnology-based approaches, have emerged as promising solutions

For people with CKD, creatinine is not excreted efficiently, leading to low creatinine levels in the urine and high creatinine levels in the blood

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Piras IS, Bleul C, Schrauwen I, Schrauwen I, Talboom J, Llaci L, Llaci L, de Both MD, Naymik MA, Halliday G, Bettencourt C, Holton JL, Serrano GE, Sue LI, Beach TG, Stefanova N, Huentelman MJ (2020) Transcriptional profiling of multiple system atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease

13 Inclusion criteria: The sample included adults (age 18 years) with 13 : 1 inpatient primary MS diagnosis or 2 outpatient MS diagnoses in any position 30 days apart in the 12 months prior to (preindex period) or 6 months following the index date First claims were recorded on or after the index date of August 20, 2020, and continuous enrollment in a commercial insurance plan 12 months before and 24 months after the index date The index date was defined as the date of the first KESIMPTA or Ocrevus claim, which was by design after the KESIMPTA US Food and Drug Administration approval on August 20, 2020 Optum Clinformatics Data Mart Database is a longitudinal database of medical and pharmacy administrative claims for patients enrolled in commercial insurance and Medicare Advantage plans in the United States

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