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BTZ induces the expression of activating transcription factor 3 and c-Jun in DRG neurons, which form a transcriptional heterodimer that upregulates CCL2 and promotes mechanical allodynia, with dose- and time-dependent variation observed in some models (Yamamoto et al., 2015

61 One of the most well-known studies of TPE, the double-blind placebo-controlled AD management by albumin replacement (AMBAR) trial, hypothesized that withdrawing plasma might flush A plaque from the brain into the plasma where it could be removed, thereby reducing AD signs and symptoms

10.1080/13607863.2020.1817311 Aging Ment

6 Consequently, targeted GSH depletion can be exploited in vitro to eliminate CLL cells

During CF pathogenesis, airway epithelial cells (IB3-1) exposed to ferric ammonium citrate and the ferroptosis inducer erastin demonstrate heightened susceptibility to ferroptosis, compared with CFTR-corrected airway epithelial cells

The ectopic expression of SLC27A5 reduced cell survival after sorafenib treatment, whereas that of SLC27A5-KO was enhanced (Fig