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This is because of their bright colors

At the same time, there are paradoxes: small dogs often produce more ROS yet still accumulate fewer pathologies, while wild canids of comparable size live longer than domestic breeds, suggesting that selective breeding has altered antioxidant capacity

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It helps to maintain the intracellular redox homeostasis to protect the cells against oxidative damage

These include flavonoids, which are divided into several subclasses or derivatives, such as isoflavones (Ku et al

Consequently, nanoformulations of antioxidant phytochemicals enhance these effects by overcoming the barriers of poor solubility, rapid metabolism, and limited bioavailability [266]