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Vertical black lines represent the genome start in the PAO1 reference against which variants were called

Common symptoms can include : Tingling / numbness in hands/feet Tiredness, exhaustion, significant fatigue Brain fog, impaired thinking and memory Flaking nails, dry skin Shortness of breath Dizziness, difficulty with co-ordination, vertigo Fluctuating weight, gastrointestinal symptoms/poor digestion Irritability, problematic sleep, depression, low libido, mood swings Diagnosing Pernicious Anaemia Due to often slow-growing, generalised symptoms, PA is often overlooked and many can be without treatment for years

nevertheless, it is still unclear which candidate provides the best balance of durability, safety, and efficacy

Ouyang BB, Zhang WL, Guang C, Xu W, Mu WM (2023) Identification and modification of enzymatic substrate specificity through residue alteration in the cap domain: a thermostable zearalenone lactonase

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Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration