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For example, in a 2009 pilot evaluation of intravenous glutathione therapy for individuals with Parkinsons disease at the University of South Florida, researchers reported that glutathione IV therapy that mildly benefited motor symptoms was well tolerated and posed no safety concerns. A 2017 case report yielded similar results

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Secondly, Mn 2+ may have potential toxicity issues, so a systematic long-term safety assessment is needed

Fluorescence intensity was quantified in 12 random cells per field using FIJI v2.1.0