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Kellogg Parsons, M.D., instructor of urology at the Brady Urological Institute at Johns Hopkins and lead researcher of the study

Serum samples from patients with RA, primary Sjgrens syndrome, and HC were analyzed using ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry

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Their research demonstrated that melatonin treatment could enhance estradiol levels by modulating the activity of steroidogenic enzymes (3-HSD and 17-HSD), thereby fostering reproductive health in individuals affected by PCOS