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Preclinical studies demonstrated that itaconate, a structural analog of succinate, inhibits ICL through covalent interaction with the catalytic cysteine residues (Cys191 of ICL1 and Cys215 of ICL2) of M.tb [30]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 175.Borsani E., Buffoli B., Bonazza V., Reiter R.J., Rezzani R., Rodella L.F

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