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The Y115F mutant isoenzyme 3-3 is about 100-fold less efficient than the native enzyme in catalyzing the addition of GSH to phenanthrene 9,10-oxide and about 50-fold less efficient in the Michael addition of GSH to 4-phenyl-3-buten-2-one

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Keklik NM, Elik A, Salgin U, Demirci A, Koer G (2019) Inactivation of Staphylococcus aureus and Escherichia coli O157:H7 on fresh Kashar cheese with pulsed ultraviolet light

Mechanistically, paclitaxel binds to the N-terminal 31 amino acids of the -tubulin subunit and decreases the threshold concentration of purified tubulin subunits which are necessary for polymerization into microtubules in vitro and elevates the fraction of tubulin subunits that assemble