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Common symptoms include: Weight loss or failure to gain (especially in puppies) Chronic diarrhoea or soft stools Lethargy and general weakness Inappetence or fussy eating Intermittent vomiting Flatulence or digestive discomfort Poor coat condition or dull fur Neurological signs (e.g., tremors, confusion, ataxia) Low folate or folate imbalance on bloodwork In puppies or young dogs with genetic B12 absorption issues, growth may be stunted , and immune function may be compromised

doi:10.1124/jpet.104.080275

[Google Scholar] Figlin 2003 Figlin E, Chetrit A, Shahar A, Shpilberg O, Zivelin A, Rosenberg N, et al

Always inform your healthcare provider of all medications and supplements youre taking

This is one reason why highly concentrated solutions are impractical for lower doses