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FcRn interacts with albumin and IgG at distinct binding sites on its heterodimeric structure, which consists of a transmembrane MHC class I-like heavy chain (HC) and a soluble, non-covalently associated 2-microglobulin (2m) subunit 52,53,54,55,56

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Data that remained non-normally distributed and/or heteroscedastic after log transformation were analyzed (not log-transformed, but still 1e13-transformed) with a KruskalWallis test, while normally distributed and homoscedastic data were analyzed with a one-way ANOVA, performed on the log-transformed data as necessary

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Schenkman E, Kenigsberg D, Kreiner D, Brenner S, Pena J and Moodie G