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Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

10.1016/j.scitotenv.2022.157665 137 SmithC

The cellular outcome of ROS exposure is influenced by dosage, duration, and the narrow concentration window in which ROS elicit beneficial signaling effects

Chemical and molecular regulation of enzymes that detoxify carcinogens

Even though mitochondrial dysfunction appears evident in ME/CFS, the causes of such dysfunction are speculative (251) and there is inconsistent evidence correlating mitochondrial dysfunction and ME/CFS (254, 283, 386, 389, 419)

The broad therapeutic potential of Ashwagandha stems from its ability to simultaneously regulate multiple cellular signaling pathways, resulting in a synergistic interplay of biological effects