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After performing in-vitro skin penetration studies by Franz diffusion cell using Porcine ear skin it was observed that about 90% and 80% of -carotene and antioxidants were penetrated in the subcutaneous layer after 12 h post application with 63% of skin retention

PTEN catalyzes the de-phosphorylation reaction of phosphatidylinositol 3,4,5-trisphosphate (PIP3) back to phosphatidylinositol 4,5-bisphosphate (PIP2) through its lipid phosphatase activity

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