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Moreover, although preclinical studies have yielded promising results, large-scale, double-blinded clinical trials remain necessary to verify the therapeutic efficacy and feasibility of these approaches in DN patients

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Vitamin B12 is typically well-tolerated, with minimal risk of side effects

10.1155/2012/296875 166 ShiX.ZhaoM.FuC.FuA

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"Injections are the preferred treatment for patients unable to absorb vitamin B12, such as patients with autoimmune-related anemia or pernicious anemia, or history of gastrectomy, which means partial removal of the stomach, or a history of bariatric surgery," Levine told InStyle