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A 2013 study from the University of Gteborg in Sweden found that 51% of test subjects on a diet including salt restrictions had seen improvements in their edema after 12 weeks

[DOI] [PubMed] [Google Scholar] Szabo S, Usadel KH

Hematologic and biochemical monitoring throughout the trials revealed no concerning patterns in blood counts, liver function tests, kidney function markers, or other laboratory parameters

10.1161/01.ATV.18.2.227 201

Oxidation destroys cell walls, and that causes substances to break down into less harmful components

Because PT-141 can slow gastric emptying, it might affect the absorption of oral medications for example, it significantly reduced the absorption of oral naltrexone in studies