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Wiad Lek (2004) 57:4535

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The secretory activity of microglia plays an essential role in the maintenance of synaptic function, the proliferation and maturation of oligodendrocytes and the recruitment of other immune cells

In order to maximize the clinical utility, various biomimetic approaches have been adopted to enhance or optimize the integrin-mediated cellular interactions and adhesion, including incorporation or surface modification with bioactive molecules or bioadhesive ECM motifs, and macro- or nano-scale patterning of the biomaterials [181]

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The original injury code with S extension links the current problem to the past trauma