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Description

Transcriptomic work by Kolomin, Shadrina, Slominsky, and Limborska at the Institute of Molecular Genetics documented differential expression of hundreds of genes after a single Semax dose in rodents, with the strongest and most reproducible changes in neurotrophin and synaptic plasticity pathways

Moreover, rats treated with 1% neohesperidin dihydrochalcone for 1 month showed reduced amygdala neuroinflammation via suppression of cAMP/PKA pathway activity, restoration of cortical 5-HT, DA, and NE levels, and reversal of anxiety- and depression-like behaviors (Jiang et al., 2023)

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Although the HGF/c-Met axis is an emerging study target, the possibility of its use in diagnosis and prognosis has been studied in addition to its mechanism in HCC