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Comment: One commenter recommended that CMS use the manufacturer-calculated specified amount for inflation rebate amounts and when calculating payment amounts for coinsurance adjustment, noting that using consistent sources across these calculations would avoid triggering inflation rebates in scenarios when there was no price increase

2 Further, there are no large, multicenter trials to evaluate safety, dosage, or long-term use of these compounds in athletes

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The commenter also raised equity concerns regarding the Rheumatoid Arthritis measure, suggesting that differences in disease severity and pain level for Black patients compared to other demographics could lead to lower MIPS scores for providers who care for these patients, particularly with the inclusion of Part D medication costs in the measure

SAF2017-82613-R), the European Research Council (ERC-2014-AdG/669622) and the Secretaria dUniversitats i Recerca del Departament dEmpresa i Coneixement of Catalonia (Grup de Recerca consolidat 2017 SGR 282)

Lumbar Disc Herniation Lumbar disc herniation (aka herniated disc) occurs when an intervertebral disc in the lower back tears or weakens, allowing its gel-like material to protrude outward and press against spinal nerves, leading to symptoms like: Lower Back Pain: Chronic and often severe lower back discomfort