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Silverstein said he decided to investigate the over-prescribing of B12 shots, because "as an internal medicine resident, I have seen many patients come into the emergency department, and they were getting B12 injections without having a really good reason for it." His study could not determine why family physicians were prescribing it inappropriately including whether it was initiated by the doctor or at the request of the patient

Potential role of new therapies in modifying cardiovascular risk in overweight patients with metabolic risk factors Obesity, 2006, PMID 16625817 Halford JC

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Vitamin B12 deficiencies can be caused by many factors, such as older age, gastrointestinal conditions, and vegan or vegetarian diets

Dosage Protocols Beginner (Weeks 1-2) Dose : 150 mcg subQ Timing : Morning, fasted Frequency : Once daily Adaptation minimizes side effects

Factors such as the form of B12 used, additional ingredients, and manufacturing standards should be considered