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[4] Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y

Swayze EE RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

Conclusion: Contrary to popular belief, endometriosis is not a problem with reproductive organs

The primary resistance mechanisms include mutations in FCY2 , encoding cytosine permease (which mediates drug uptake), and mutations in FCY1 , encoding cytosine deaminase (required for 5-FC activation) (Longley et al., 2003