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Main limitation: selectivity figures (such as an in-vitro ~11.7-fold preference for senescent cells) come from cell models, not humans

Iron is the key oxygen-binding element in hemoglobin, a red blood cell component that allows for oxygen transport and dispersion throughout the body

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9 The point mutation H1069Q is the most common ATP7B mutation in patients from Central, Eastern and Northern Europe and 5080% of WD patients from these countries carry at least one H1069Q allele