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The purified enzyme was shown to be active with seven nephrotoxic cysteine S -conjugates derived from halogenated alkenes (Kraus et al., 2000)

mBio 16 , e0167701625 (2025)

COVID-19 appears to alter glutathione generation patterns related to aging, with younger individuals displaying signs of oxidative damage typically seen in older age groups

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This causes inhibition in cell proliferation and enhancement in apoptosis