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Valko M, Morris H, Mazr M, Rapta P, Bilton RF (2001) Oxygen free radical generating mechanisms in the colon: do the semiquinones of vitamin K play a role in the aetiology of colon cancer

This culminates in (1) axo-dendritic pathology coupled to loss of synaptic function, (2) impaired mitochondrial dynamics coupled with altered energy homeostasis, and (3) impaired dopamine metabolism, all of which contribute to further RNS imbalance