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While it is generally accepted that low plasma SHBG levels are a sensitive predictive biomarker of increased risk for cardiovascular disease 6,7 and type 2 diabetes 3 there is evidence that genetic differences associated with high versus low plasma SHBG levels protect or predispose individuals to type 2 diabetes, respectively 3

After a recovery period of 3 days, AT-NC and AT-SIRT3OE mice were randomly separated into two groups, each 6 mice, and fed with an HFD (calorie 4.5 kcal/g, Trophic Animal Feed High-Tech Co., Nantong, Jiangsu, China) and regular chow diet (RD, calorie 2.35 kcal/g), respectively, for consecutive 13 weeks [35]

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Pediatr Int 44:7073 Ibarra-Sifuentes HR, Del Cueto-Aguilera , Gallegos-Arguijo DA, Castillo-Torres SA, Vera-Pineda R, Martnez-Granados RJ et al (2017) Levocarnitine decreases intradialytic hypotension episodes: a randomized controlled trial

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