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Weber T, Kim HU (2016) The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production

10.1002/glia.23667 237 WagstaffL

These unstable molecules break down healthy skin cells

In the vehicle controls we observed a significant depletion of sgRNAs targeting commonly accepted core essential genes, suggesting the screen had sensitivity detecting genetic perturbations (Supplementary Fig

Common bottlenecks include: first, the need to confirm their long-term efficacy and safety in the context of chronic metabolic diseases such as diabetes, which differs significantly from acute injury models

as phase 2 and 3 data mature, it may reshape the therapeutic landscape for anovulatory PCOS significantly