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Conversely, elevated levels of glycoprotein acetyls, apolipoprotein B, and cholesterol correspond to a higher risk of cardiovascular issues

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In another study focussed on the treatment of mice with vaginal candidiasis (yeast infection), subjects were given an intravaginal GSE solution every other day across an 8-day period

Moreover, a key challenge is balancing the desired anti-tumor immune effects with potential systemic metabolic side effects, such as dyslipidemia, which has been observed with some FXR agonists (132)