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doi: 10.1038/s41559-018-0569-4 120 GrandinT

10.1161/01.CIR.99.16.2138 74

promotes optimal cell function and helps eliminate toxins for overall well-being

In murine models of NAFLD, nicotine exposure downregulated the expression of CDGSH iron-sulfur domain 3 (CISD3), leading to impaired mitochondrial function

On the other hand, H 2 S produced in cytosol enhances the activity of cystine/glutamate antiporter to increase the transport of cystine, which is reduced to cysteine and used to produce GSH in cells 9