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Then IgG or indicated antibodies (2 g) were added to supernatants for 4 h at 4 C, captured by adding the protein A/G agarose (Pierce, 20421) before incubation for 4 h at 4 C and the beads were washed five times with IP buffer containing 500 mM NaCl

Regular glutathione is often destroyed by stomach acid during digestion, meaning very little reaches your cells

Keap1 functions as an interacting partner of Nrf2, binding with Nrf2 to facilitate its degradation and exert a negative regulatory influence on Nrf2 activity

This difference in average viability suggests an increased cellular uptake of oxaliplatin in the 90 min treated MCTS compared to those treated for 30 min

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104,105 A study demonstrated that oxidative stress-induced Nrf2 promotes drug efflux by upregulating ABCG2, as observed in biliary tract cancer cells