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Glutathione (GSH) is an endogenous tripeptide (-L-glutamyl-L-cysteinyl-glycine) and the most abundant intracellular antioxidant in mammalian cells

Purine metabolism Metabolites from the PPP, such as ribose-5-phosphate, can be shunted into creation of purines and pyrimidines

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Peer review Peer review information Nature Reviews Molecular Cell Biology thanks Michael Murphy, Navdeep Chandel, Isaac Harris and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

More importantly, nano-PROTAC could degrade 74% of the AR splice variant AR-V7 protein, showing the potential ability to overcome drug resistance

A growing number of studies have broadly examined the link between inflammation and cancer, supporting its role in promoting tumor initiation, progression, and metastasis