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R3 is selected from the group consisting of a hydrogen atom and an R4-CO (acyl) group, wherein R4 is an alkyl (e.g., C 1 -C 20 ) or aryl (e.g., C 6 -C 9 ) group

The RnB protocol has been found to be highly effective in reversing the symptoms of CFS (RnB protocol) Creatine supplementation has also proven to have some success in some individuals (Allen, 2012)

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Media was replaced 24 h later and confluent cells were treated with 2 l of supernatant harvested from BMDM experiments

Liu L, Kim S, Buckley MT, Reyes JM, Kang J, Tian L, Wang M, Lieu A, Mao M, Mateo-Rodriguez C, Ishak HD, Jeong M, Wu JC, Goodell MA, Brunet A, Rando TA (2023) Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging