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These findings underscore the significance of systemic inflammation in persistent VCD associated with long COVID

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33,34,35,36,37 One study suggests that length of time from diagnosis of cognitive impairment is important for response rate, in that patients who had experienced symptoms for less than 12 months improved on B12, whilst those with symptoms for more than 12 months continued to decline

Methionine, inositol, and choline are commonly associated with fat metabolism and liver function, while vitamin B12 is commonly associated with energy production and nervous system support