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Its prevalence is estimated as 9.6/100,000 persons for men and 37.8/100,000 persons for women (2, 3)

The secretion is inhibited by Somatostatin (SS) and stimulated by Growth Hormone Releasing Hormone (GHRH) and ghrelin

Legal status (US): Tesamorelin is FDA-approved under the brand names Egrifta and Egrifta WR, manufactured by Theratechnologies, specifically to reduce excess visceral abdominal fat in HIV-infected patients with lipodystrophy

Obesity, uncontrolled diabetes, regular alcohol use and a high-calorie diet can all contribute to high blood triglyceride levels. Tesamorelin can help you lower your triglycerides to a healthy level of ~150 mg/dL, according to physicians at John Hopkins Medicine: Tesamorelin decreases abdominal fat by a modest 14-18% and significantly reduces triglycerides and non-HDL cholesterol in HIV+ pts with lipodystrophy

It is available only by prescription, and outside that approved indication it is prescribed off-label and often dispensed as a compounded preparation through 503A/503B compounding pharmacies for bodybuilding, fat-loss, or anti-aging purposes, uses the FDA has not evaluated or approved

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