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To perceive and ward off potential pathogens, plants have developed a highly resilient, two-tiered innate immune detection-and-response system: pattern recognition receptor (PRR)-mediated pattern-triggered immunity (PTI) and intracellular nucleotide-binding domain leucine-rich repeat receptor (NLR)-mediated effector-triggered immunity (ETI) 1,2,3

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Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase on the APE1-DNA interaction

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After the pesticide was banned, lawmakers and biologists undertook a significant effort to protect the few eagles that remained and boost their chances of survival