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Common reasons for deficiency include: Low intake particularly diets low in whole grains, legumes, leafy greens or animal products Gut health issues like low stomach acid, SIBO, coeliac disease, IBD, or other factors affecting absorption Medications such as the contraceptive pill, metformin or antacids, which can deplete B vitamins Chronic stress increases demand for certain b vitamins, including B5 and B6 Vegan or vegetarian diets higher risk of B12 deficiency, which can be corrected through supplementation Genetic reasons some mutations on certain genes can increase a persons need for B vitamins This is why I always recommend testing before supplementing

In addition to serving as an energy supply, KBs also serve as substrates for the production of lipids in the brain, such as myelin (Cunnane and Crawford, 2014)

Decreased Intake issues: A vegan or vegetarian diet with no animal products Poor Absorption Issues Medications that block absorption of B12 Pernicious anemia Auto-immune disorders An Helicobacter pylori (H