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Of note, the relative abundance of the Parasutterella genus, which was significantly enriched in both the vehicle- and 5A-1MQ-treated animals transitioned from WD to LD compared to both the WD and LD control groups, was observed to be significantly correlated (either positively or negatively) with 30 EWAT metabolites, both with and without outliers included

and does not achieve its principal intended action in or on the human body by pharmacological, immunological or metabolic means, but which may be assisted in its function by such means. Software as Medical Device (SaMD): An SaMD in Australia is defined as a software intended to be used for one or more medical purposes that perform these purposes without being part of a hardware medical device. In Vitro diagnostic Device (IVD) An in vitro diagnostic medical device (IVD) is a reagent, calibrator, control material, kit, specimen receptacle, software, instrument, apparatus, equipment or system, whether used alone or in combination with other diagnostic goods for in vitro use

The NHS explained: "It happens when the blood supply to the nerves is cut off." If not enough oxygen is reaching nerves in the extremities, such as the hands and feet, then pins and needles can occur

Water Res 129:110

doi: 10.1016/j.jconrel.2014.08.016