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Finally, we introduced overexpression of either wildtype or mutant METTL16 in different DDX3X knockdown cells (Fig

Collectively, these results demonstrate that targeting OXPHOS is a metabolic vulnerability in metastatic ER + BC, including endocrine-resistant tumours

Pain in the shoulder, commonly reported by patients with PD 15 , 43 , may be the first symptom in 2-8% and may even precede the onset of motor symptoms 44

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Supporting endogenous release rather than supplying exogenous GH, it offers a more physiologic, regulated approach

Correct mutations and sequences were confirmed for all constructs by sequencing both strands (SEQ-IT)