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BMC Genomics 25:236

RSL3 (a GPX4 inhibitor) inactivates GPX4 and induces glycolytic dysfunction in glioma cells with reduced ATP and pyruvate content as well as HKII, PFKP, and PKM2 protein levels, which in turn induces ferroptosis ( TP53 encodes p53 promoting cell cycle arrest, senescence, and apoptosis, which are three canonical functions of p53 involved in tumor suppression

G.Diaz-GalvanP.Graff-RadfordJ.et al

Nuclear lamins: key regulators of nuclear structure and activities

Conventional extraction methods (e.g., solvents, maceration, Soxhlet) have significant limitations

Notably, cMono and mDCs from CHB patients exhibited significantly slower uptake of ICs compared to healthy donors