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6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance

doi: 10.3390/genes13030466 78 PhilipPAAzarIXiuJHallMJHendifarAELouEet al

Treatment of phLF and phBEC with TGF-1, TNF-, and menadione For treatment of phLF, cells were seeded at a density of approximately 20,000 cells/cm 2 , starved for 24 hours in DMEM/F12 with 0.5% FBS and 100 nM sodium selenite, followed by treatment with 2 ng/ml TGF-1 (R&D Systems, Minneapolis, MM, USA), 10 ng/ml TNF- (PeproTech, Rocky Hill, NJ, USA), and 10 M menadione (Sigma-Aldrich) in starvation medium for the indicated time points

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Therefore, mitochondrial transfer has therapeutic potential in regulating immune cell function in RA (8183)

We analyzed the averaged taxonomic compositions of the microbiome taxonomic profiling (MTP) set and Fusobacteriaceae and Bacteroidales was more prominent in patients who survived and also Fusobacterium nercogenes was abundant in patients who survived while Rothia mucilaginosa was more abundant in patients who did not survive