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This accumulation can damage performance of pancreatic islet -cells through lipotoxicity, exacerbate impaired insulin action, impair glucose metabolism, and ultimately lead to hyperglycemia and hyperinsulinemia, creating a vicious cycle

In some people, nasal congestion can also cause problems such as runny nose, nasal discharge, and cough

Benefits may plateau after 6-12 months as optimization is reached

Personalized, evidence-based exercise interventions hold great promise as adjunct therapies in BC care, but more rigorous research is necessary to unlock their full potential

Its toxicology is unknown

Microbial metabolites like SCFA and Trp derivatives can activate AhR and its target genes, including IL-6, IL-22, prostaglandin G/H synthase 2 (PTGS2), vascular endothelial growth factor A (VEGFA), and cytochrome P450 1 A1 (CYP1 A1) in the intestine or liver