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Another avenue is advanced surface engineering to create coatings that are selectively permeable to contaminants but act as a robust physical and chemical barrier to biological macromolecules, thus preventing the non-specific interactions that initiate toxicity.186 Fig

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doi:10.1016/j.abb.2019.01.011 ^ Matschinsky F.M., Wilson D.F

In a multicenter, randomised, double-blind, placebo-controlled trial of AD from 2007 to 2012, vitamin E was found to significantly reduce cognitive performance in patients with mild to moderate AD

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Conventional medical approaches to treating Parkinson's disease aim to replace the lost dopamine, but fall short of addressing the ongoing destruction of dopaminergic neurons