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2 mg/week: 5 weeks per vial 4 mg/week: 2.5 weeks per vial 5 mg/week: 2 weeks per vial 8 mg/week: 1.25 weeks per vial 10 mg/week: 1 week per vial This creates a planning challenge

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Additionally, ALA enhanced the level of PPAR-, facilitated the nuclear translocation of Nrf2 and inhibited NF-B activation, leading to increased antioxidant levels and reduced inflammation

In this model, cells are incubated in a glucose-free medium under deoxygenated atmosphere in order to mimic the conditions occurring during an ischemic stroke (Tasca et al., 2015)