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2 Drugs targeting the ubiquitin-proteasome system have drastically improved myeloma treatment

Bansal 1 , (1)Icahn School of Medicine at Mount Sinai, (2)University of Minnesota, (3)Virginia Commonwealth University, (4)Pennsylvania State University, (5)University of Michigan Hospitals and Health Centers Background: Weight loss is the cornerstone of treatment in nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH)

Eur J Endocrinol (2000) 142(3):2315

European Review for Medical and Pharmacological Sciences

G.NetzD

Renal tubular cell injury and the defective mitochondria and other intracellular organelles are evidence of aggravated CaOx crystal retention inside the renal tissue, which is considered as one of the important steps for kidney stone development (Govindaraj and Selvam, 2002