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2022 Apr 5;34(4):595-614.e14

Cancer 12 (23), 31943200

Reviews in Endocrine and Metabolic Disorders, 23(5), 979994

Keap1, an E3 ubiquitin ligase and an inhibitor of the transcription factor nuclear erythroid-related factor 2 (NRF2), has recently been identified as a target of protein succination and consequent inactivation, which led to the induction of NRF2 and a potent antioxidant response 5,7

However, this approach is not suitable for non-hyaluronic acid fillers