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To obtain the EC 50 value, the normalized BRET response (normalized BRET ratio to untreated cells) was fitted with the DoseResponse function of Origin 2018

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Genetic variations in IREB2 have been associated with increased Alzheimers disease risk, underscoring its role in AD pathogenesis (203)

HBV patients hospitalized with alcoholic liver disease (ALD) alone, without cirrhosis, had a significantly increased HCC risk (HR 6.4)

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